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Simon Middleton's side enjoyed a marvellous first 40 minutes, scoring four tries through Jess Breach, Poppy Cleall, Kelly Smith and Breach again - the latter two of which came with Vickii Cornborough in the sin-bin.
Safi N'Diaye, Pauline Bourdon twice and Romane Menager scored in reply for France during the second period to earn a bonus-point, but it was far too little.
Poppy Cleall of England touches down for the fifth try In a contest which was widely billed as a title decider following impressive wins for both sides in the opening round of fixtures, England raced into a lead at half-time and survived a brief French rally to run out comfortable winners.
The home side thought they had opened the scoring in the fifth minute when full-back Sarah McKenna breezed past two opponents to touch down under the posts, but following an intervention from the TMO the try was ruled out after Poppy Leitch was penalised for blocking Menager in the scrum.
Leanne Riley passes the ball against France It did not take for long for England to break the deadlock however, Breach touching down in the 11th minute after collecting a pinpoint cross-field kick from fly-half Katy Daley-Mclean, whose conversion made her the first English woman to pass the landmark of international points.
Cleall then crashed over from close range after winger Kelly Smith had been stopped just short of the line and England increased their lead through Breach's second score despite Cornborough being shown a yellow card for a high tackle.